Hironori Takahashi Selected Research

Pre-Eclampsia (Preeclampsia)

1/2024	Gasdermin D regulates soluble fms-like tyrosine kinase 1 release in macrophages.
12/2023	Automated electrochemiluminescence immunoassay for serum PlGF levels in women with singleton pregnancy at 9-13 weeks of gestation predicts preterm preeclampsia: a retrospective cohort study.
10/2022	Pregnancy in a patient with caudal regression syndrome following continent bladder reconstruction.
1/2022	Elevated S100A9 in preeclampsia induces soluble endoglin and IL-1β secretion and hypertension via the NLRP3 inflammasome.
1/2020	Interstitial Pregnancy in the Third Trimester with Severe Preeclampsia: A Case Report and Literature Review.
1/2020	Difficulty of predicting early-onset super-imposed preeclampsia in pregnant women with hemodialysis due to diabetic nephropathy by serum levels of sFlt-1, PlGF, and sEng.
12/2019	Preeclamptic patient-derived circulating cell-free DNA activates the production of inflammatory cytokines via toll-like receptor 9 signalling in the human placenta.
10/2018	Serum soluble LIGHT in the early third trimester as a novel biomarker for predicting late-onset preeclampsia.
1/2018	Galectin-1 as a novel risk factor for both gestational hypertension and preeclampsia, specifially its expression at a low level in the second trimester and a high level after onset.
1/2017	Re: Serious maternal complications in relation to severe pre-eclampsia: a retrospective cohort study of the impact of hospital volume; Severe maternal morbidity requires regionalisation of obstetric critical care; Guilt, blame and litigation: can an overenthusiastic 'safety culture' cause harm?: Maternal mortality: the heavy psychological burden on centre obstetricians.

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Hironori Takahashi Research Topics

Disease

16	Hemorrhage 02/2024 - 05/2014
15	Placenta Previa 12/2022 - 05/2014
10	Pre-Eclampsia (Preeclampsia) 01/2024 - 01/2017
9	Placenta Accreta 01/2023 - 06/2010
9	Heart Failure 06/2022 - 09/2019
8	Inflammation (Inflammations) 01/2024 - 08/2017
8	ST Elevation Myocardial Infarction 06/2022 - 09/2020
6	Death (Near-Death Experience) 06/2022 - 09/2020
6	Postpartum Hemorrhage 01/2019 - 06/2010
5	Pregnancy Complications 11/2021 - 08/2017
4	Macular Degeneration (Age-Related Maculopathy) 01/2024 - 09/2023
4	Infections 01/2023 - 08/2012
4	Cardiovascular Diseases (Cardiovascular Disease) 06/2022 - 01/2021
4	Hypertension (High Blood Pressure) 01/2022 - 03/2017
3	Disease Progression 10/2023 - 08/2012
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2023 - 01/2012
3	Obesity 06/2020 - 08/2017
3	Hemolysis 01/2019 - 11/2015
3	False Aneurysm (Pseudoaneurysm) 01/2019 - 08/2017
2	Diabetic Ketoacidosis (Ketoacidosis, Diabetic) 10/2023 - 03/2017
2	Cysts 09/2023 - 01/2019
2	Abdominal Pain (Pain, Abdominal) 09/2023 - 01/2016
2	Prostatic Neoplasms (Prostate Cancer) 02/2023 - 08/2021
2	Fetal Growth Retardation (Intrauterine Growth Retardation) 07/2022 - 08/2021
2	Hypoxia (Hypoxemia) 01/2022 - 01/2018
2	Neoplasms (Cancer) 01/2022 - 01/2009
2	Myocardial Infarction 01/2022 - 01/2021
2	Atrial Fibrillation 01/2022 - 09/2019
2	Coronary Artery Disease (Coronary Atherosclerosis) 07/2021 - 01/2018
2	Acute Coronary Syndrome 01/2021 - 01/2018
2	Headache (Headaches) 01/2021 - 03/2017
2	Infarction (Infarctions) 10/2020 - 09/2020
2	Maternal Obesity 06/2020 - 08/2017
2	Neonatal hemochromatosis 01/2020 - 10/2016
2	Cholangitis 03/2019 - 11/2015
2	Thrombocytopenia (Thrombopenia) 01/2019 - 05/2017
2	Rupture 11/2017 - 02/2017
2	HELLP Syndrome 03/2017 - 11/2015
2	Myalgia 02/2017 - 01/2017
2	Myositis (Idiopathic Inflammatory Myopathies) 02/2017 - 01/2017
2	Diabetes Mellitus 02/2013 - 01/2012
1	Hematoma 02/2024
1	Birth Weight (Birth Weights) 02/2024
1	Intellectual Disability (Idiocy) 01/2024
1	Epilepsy (Aura) 01/2024
1	Menkes Kinky Hair Syndrome (Menkes Disease) 01/2024
1	Anovulation 11/2023
1	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 11/2023
1	Hyperglycemia 10/2023
1	Hematuria 10/2023
1	Anti-Glomerular Basement Membrane Disease (Goodpasture's Syndrome) 10/2023

Drug/Important Bio-Agent (IBA)

8	omega-Chloroacetophenone (Mace)IBA 06/2022 - 09/2020
7	CytokinesIBA 09/2023 - 08/2017
5	InflammasomesIBA 01/2022 - 08/2017
4	EnzymesIBA 10/2023 - 11/2015
4	Hemostatics (Antihemorrhagics)IBA 12/2022 - 03/2017
4	Glucose (Dextrose)FDA LinkGeneric 07/2021 - 03/2017
4	Methotrexate (Mexate)FDA LinkGeneric 04/2020 - 01/2017
3	brolucizumabIBA 01/2024 - 09/2023
3	Hemoglobins (Hemoglobin)IBA 10/2023 - 02/2020
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 08/2017
3	Proteins (Proteins, Gene)FDA Link 11/2021 - 02/2014
3	Immunoglobulins (Immunoglobulin)IBA 01/2020 - 01/2005
2	Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA 01/2024 - 01/2020
2	faricimabIBA 01/2024 - 10/2023
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 12/2023 - 01/2020
2	RNA (Ribonucleic Acid)IBA 10/2023 - 08/2018
2	Insulin (Novolin)FDA Link 10/2023 - 12/2017
2	landiololIBA 01/2022 - 09/2019
2	EndoglinIBA 01/2022 - 01/2020
2	Blood Glucose (Blood Sugar)IBA 07/2021 - 12/2017
2	Interleukin-8 (Interleukin 8)IBA 04/2019 - 08/2017
2	Ritodrine (Yutopar)FDA Link 01/2018 - 02/2017
2	CreatinineIBA 02/2017 - 07/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2016 - 08/2012
2	AlbuminsIBA 02/2013 - 01/2012
1	CopperIBA 01/2024
1	Ceruloplasmin (Ferroxidase)IBA 01/2024
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2024
1	Hormones (Hormone)IBA 11/2023
1	AntibodiesIBA 10/2023
1	antiglomerular basement membrane antibodyIBA 10/2023
1	HLA Antigens (Human Leukocyte Antigens)IBA 10/2023
1	Glutamate Decarboxylase (Decarboxylase, Glutamate)IBA 10/2023
1	COVID-19 VaccinesIBA 10/2023

Therapy/Procedure

28	Cesarean Section (Caesarean Section) 02/2024 - 05/2014
13	Hysterectomy 02/2024 - 06/2010
8	Sutures (Suture) 12/2022 - 01/2015
6	Therapeutics 01/2024 - 11/2015
4	Percutaneous Coronary Intervention 06/2022 - 09/2020
3	Laparotomy 09/2023 - 01/2016
3	Radiotherapy 02/2023 - 01/2009
3	Uterine Artery Embolization 02/2020 - 06/2010
2	Laser Therapy (Surgery, Laser) 07/2022 - 05/2012
2	Patient Readmission 01/2022 - 10/2020
2	Drug Therapy (Chemotherapy) 03/2019 - 01/2009
2	Conservative Treatment 01/2018 - 01/2009
2	Stents 05/2017 - 11/2015
2	Glycemic Control 02/2013 - 01/2012
1	Immunomodulation 10/2023